Peripheral intravenous therapy is a common nursing procedure in hospitalized patients. Superficial thrombophlebitis remains one of the most frequent complications associated with intravenous cannulation. Effective nursing interventions are essential to reduce inflammation, pain, and patient discomfort.

Aim: To evaluate the effectiveness of Glycerin Magnesium Sulphate (GMS) dressing on superficial thrombophlebitis among patients receiving intravenous therapy.

Methods: A quantitative quasi-experimental pre-test and post-test design was adopted. Sixty patients with superficial thrombophlebitis receiving intravenous therapy were selected using convenience sampling. Jackson’s Visual Infusion Phlebitis Scale was used to assess thrombophlebitis severity before and after intervention. GMS dressing was applied twice daily for two days.

Results: The mean pre-test thrombophlebitis score was 4.05 ± 0.82, which reduced to 1.52 ± 0.59 after intervention. The paired t-test value was 19.1 (p < 0.05), demonstrating a statistically significant reduction in thrombophlebitis severity.

Conclusion: GMS dressing was highly effective in reducing superficial thrombophlebitis among patients receiving intravenous therapy and can be incorporated into routine nursing practice.