Background: Infant care practices play a vital role in reducing infant morbidity and mortality. Mothers residing in tribal communities often face barriers such as limited health awareness, cultural beliefs, and inadequate access to healthcare services, which influence infant care practices.

Objectives: To assess infant child care practices and evaluate the effectiveness of an interventional package on knowledge regarding infant child care among mothers in a selected tribal community.

Methods: A longitudinal research design was adopted among mothers having infants residing in a selected tribal community of Odisha. Baseline knowledge and infant care practices were assessed using structured questionnaires and observational checklists. An interventional package consisting of health education, demonstrations, and counseling was administered. Pre-test and post-test knowledge scores were compared using appropriate statistical analysis.

Results: Baseline findings revealed inadequate maternal knowledge regarding infant care practices. Following intervention, a significant improvement in knowledge scores was observed. The intervention demonstrated effectiveness in enhancing maternal awareness regarding breastfeeding, hygiene, immunization, and illness prevention.

Conclusion: Structured educational interventions significantly improve maternal knowledge and infant care practices. Community-based nursing interventions are essential to promote safe childcare practices in tribal populations.