Ventilator-associated pneumonia (VAP) is a frequent infection in ICU patients on mechanical ventilation, commonly occurring after intubation. Effective oral care within a care bundle can lower VAP rates by 60%. Nurses play a vital role in VAP prevention, but gaps in knowledge may affect adherence to guidelines. A study assessed GNM nursing students' understanding of VAP care bundles, revealing that knowledgeable nurses can better mitigate patient risks. A pre-experimental study demonstrated that a structured teaching program significantly increased GNM students' knowledge about VAP, with post-test scores rising significantly from a mean of 7.65 to 15.02, confirming the program's effectiveness and rejecting the null hypothesis. The study involved 40 students with varied clinical exposure, predominantly female, using a one-group pretest post-test design to measure knowledge improvement.