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VOL. 7, ISSUE 4 (2025)
Mitochondrial health and youthful aging: A mechanistic and translational perspective
Authors
Dr. Zahid Hussain Deshwali, Dr. Vikas Sharma
Abstract
Mitochondria are essential organelles responsible for energy
production, metabolic regulation, and cellular homeostasis. Their optimal
function is increasingly recognized as a cornerstone of healthy aging and
longevity. Mitochondrial dysfunction contributes to the progression of
age-related diseases and physiological decline through mechanisms involving
oxidative stress, impaired bioenergetics, altered mitochondrial dynamics, and
defective mitophagy. Mitochondrial health is central to maintaining youthful
physiology and delaying the onset of age-related diseases. As the key
regulators of bioenergetics, redox balance, and cell survival, mitochondria
determine cellular vitality and systemic function. Mitochondrial dysfunction
contributes to diverse age-associated conditions, including neurodegeneration,
sarcopenia, metabolic disorders, and premature aging syndromes.
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Pages:82-84
How to cite this article:
Dr. Zahid Hussain Deshwali, Dr. Vikas Sharma "Mitochondrial health and youthful aging: A mechanistic and translational perspective". International Journal of Nursing and Health Research, Vol 7, Issue 4, 2025, Pages 82-84
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