Background: Around 0.5% to 2% of people worldwide suffer with vitiligo, a chronic skin disorder marked by depigmented lesions brought on by the autoimmune loss of melanocytes.

Aim: The purpose of the study was to evaluate vitiligo patients' burden and level of understanding.

Research design: This study employed a descriptive cross-sectional research approach.

Sample: For this investigation, a convenient sample of 80 vitiligo patients was employed. Setting: Tools for gathering data: The data was gathered using three instruments, Tool (I): Questionnaire for structured interviews, Tool (II): Vitiligo disease knowledge evaluation sheet, The Vitiligo Impact Patient Scale is tool (III).

Results: 90% of the patients in the study had inadequate knowledge, while 10% had adequate knowledge. The largest percentage experienced significant burdens in the following areas: relationships & sexuality, economic constraints, psychological effects on daily life, and care & management of disease (50%, 61.2%, and 47.5%, respectively).