Introduction: Acute appendicitis is a common emergency in general surgery and globally appendectomy is at the top of emergency surgical procedures. Evidence suggests appendectomy is the first-line treatment for acute appendicitis. About 9% of patients develop complications after appendectomy, leading to a long hospital stay and recurrent surgery among others^. Surgical site infection (SSI) is a common complication of appendectomy. Nursing theories can be beneficial in care of practice of patients with appendectomy by collaborated multidisciplinary approach incorporating scientific principles and knowledge.