Introduction: Background of the study: Cardiovascular disease (CVD) is the leading cause of death worldwide. The prevalence of coronary artery disease (CAD) a major contributor to CVD is related to the increasing prevalence of modifiable risk factors, previous studies identified diabetes mellitus, hypertension, hyper cholesterolemia, smoking, alcohol consumption, obesity and sedentary lifestyle as risk factors. However, certain risk factor may predominant in certain regions. Smoking is the main determinant of ischemic heart disease (IHD) amongst the east Indians of Bangalore, India and population of certain Arab countries.

Objectives: The objective of the study was to assess the effectiveness of Structured Teaching Programme on knowledge regarding early signs and immediate management of myocardial infarction among the ANM students. A descriptive quantitative approach and pre-experimental, one group pretest posttest design was used to carry out this study. The students were selected by Non-probability purposive sampling technique where data was collected by using self-administered questionnaire. The analysis was done by using inferential statistics

Results: The study found that the knowledge on early signs and immediate management of myocardial infarction among ANM was 45.5% to overall mean percentage of knowledge. The mean knowledge score is 13.95+6.65. There is no significance association between knowledge scores into age in years, gender, marital status, education, and teaching experience (years) & source of information of school teachers working in selected Nursing schools in Amravati.