This study is to highlight practical recommendations in a concise format designed to assist acute-care hospitals in implementing and prioritizing their central line-associated bloodstream infection (CLABSI) prevention efforts.

Objectives: To assess the   Catheter Associated Blood Stream Infection (CLABSI) among patients with central line catheter in experimental and control group To evaluate the effectiveness of   Care bundle on prevention of catheter associated blood stream infection among patients with central line catheter in experimental and control group.   To associate the level of blood stream infection among patients with central line catheter and their demographic variables in experimental and control group. Methodology: Quantitative research approach. A non probability purposive sampling technique is used.The research design adopted for this study was quasi experimental non randomized control group post test only design.. Sample of the study include patients with central line catheter admitted in ICU and those who fulfill the inclusion criteria and present during the time of the data collection at Dhanvantri Critical Care Center, Erode.