Introduction: Text neck syndrome, also known as repeated stress discomfort, is an ailment caused by prolonged use of mobile devices for watching or frequent messaging. Typer’s Thumb also known as de Quervain’s Tenosynovitis is a condition in which the tendons that move your thumb become inflamed. Mobile phone usage is steadily expanding, and individuals are spending longer periods on them, Children and teenagers are expected to spend 5 to 7 hours each day on their cell phones, and portable gadgets, reading and texting with their necks stretched forward. Aim: The aim of this objective was to assess the knowledge of text-neck syndrome and typer’s thumb among the undergraduate nursing students and to find out the association between the knowledge regarding text neck syndrome and Typer’s thumb among undergraduate students with their selective demographic variables. Methodology: A pre-test descriptive design was chosen with convenient sampling technique. Types of study: Quantitative Research Approach. Types of Participants: Undergraduate nursing students. Setting: Sharda University, Greater Noida. Outcome: The study showed Nursing students had average knowledge regarding text-neck syndrome and typer’s thumb implying that there is need for more awareness regarding its knowledge, uses and implementations.